Alkahest Announces Initiation of Two Phase 2 Clinical Trials of ALK4290 in Age-Related Macular Degeneration
SAN CARLOS, Calif., May 14, 2018 /PRNewswire/ — Alkahest Inc. (“Alkahest”), a clinical-stage biotechnology company focused on developing innovative therapies to treat age-related diseases, today announced the initiation of two Phase 2 clinical trials of ALK4290 in patients with the wet form of age-related macular degeneration (AMD).
“We are excited to advance ALK4290, which has demonstrated promising preclinical activity in animal models as an oral monotherapy agent,” said Sam Jackson, Alkahest’s Chief Medical Officer. “Oral dosing is particularly advantageous from a patient convenience perspective when compared to the standard of care, which is currently administered via intravitreal injection. We look forward to continuing to work with clinical experts, patients and their families as we pursue this novel approach to the treatment of the leading cause of blindness in adults.”
The ALK4290-201 study is a single-arm open-label Phase 2 clinical trial designed to evaluate the therapeutic effects and safety of a 6-week oral treatment regimen of ALK4290 in patients with newly diagnosed wet AMD. The ALK4290-202 study is a single-arm open-label Phase 2 clinical trial designed to evaluate the therapeutic effects and safety of a similar treatment regimen in patients with refractory wet AMD…..
Source: Cision PR Newswire