Fewer Visits for Aflibercept Injection With Observe and Plan
by: Damian McNamara
COPENHAGEN — An “observe-and-plan” regimen for scheduling aflibercept injections improves visual acuity in patients with neovascular age-related macular degeneration, and could improve the efficiency of clinics treating these patients, a prospective 2-year study suggests.
“The take-home message is that the observe-and-plan regimen in neovascular AMD allows for good visual results with the usual number of injections, yet with a strongly reduced number of visits,” said investigator Irmela Mantel, MD, from the University of Lausanne in Switzerland.
The observe part of the regimen relies on a prediction of the need for retreatment. After three loading doses of aflibercept, patients are observed to predict the likely interval for disease recurrence.
This predication assessment is used in the plan part of the regimen to determine the spacing of the next three injections (with an interval from 1 month to 3 months). During clinical assessments, performed at least every 6 months, clinicians determine the effectiveness of the treatment and adjust the plan as needed.
This allows “for better investment of resources or the management of more patients with the same resources,” Dr Mantel told Medscape Medical News.
She presented 2-year data for 99 eyes here at the European Society of Retina Specialists 16th EURETINA Congress…….
Read more: http://www.medscape.com/viewarticle/868656