Cell transplantation ( stem cells) are being study to see if they can return daylight to the blind. The successful transplantation of cone-like photoreceptors into the retina of recipient mice with disrupted daylight vision was successful. It is being done on mice only at this time.-MDA

Degeneration or loss of the light-sensitive cells of the retina, the so-called photoreceptors, inevitably leads to vision impairment and blindness with no curative therapy currently available. On of the main causes for disability in industrialized societies is the loss of cone photoreceptors that are responsible for daylight vision.

The team of Professor Marius Ader of the DFG-Research Center for Regenerative Therapies Dresden – Cluster of Excellence at the TU Dresden (CRTD) in collaboration with Dr. Günther Zeck of the Natural and Medical Sciences Institute (NMI) at the University of Tübingen, now report the successful transplantation of cone-like photoreceptors into the retina of recipient mice with disrupted daylight vision. They demonstrated that donor cells correctly integrated in the host tissue that resulted in recovered signal processing under daylight conditions. These results represent an important step towards the development of cell-based strategies for the treatment of retinal degenerative diseases. The study was recently published in the journal „Stem Cells“ (DOI: 10.1002/stem.1824.).

Human daylight vision depends on cone photoreceptors and their degeneration results in severe visual impairment as observed in several eye diseases including age‐related macular degeneration, cone‐rod dystrophies, or late stage retinitis pigmentosa. The adult mammalian retina, including humans, does not intrinsically regenerate and thus dying photoreceptors result in permanent vision loss with no treatments currently available. Several therapeutic approaches are currently being developed to treat retinal degenerative diseases………

Read more:  http://www.healthcanal.com/medical-breakthroughs/56881-cell-transplantation-allows-mice-to-see-again-in-daylight.html

Source: Health Canal

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