Central corneal thickness associated with visual field progression

by: Tan HK

Researchers reported that thin central corneal thickness was associated with visual field progression in primary angle closure glaucoma in a study recently published in the Asia-Pacific Journal of Ophthalmology.

Tan and colleagues conducted a combined cross-sectional, prospective study of primary angle closure glaucoma (PACG) and primary angle closure (PAC) to assess any relationship between visual field progression and CCT.

Researchers used a microscopy SP-200P (Topcon Corp.) to measure CCT in the participants. The study included 105 total eyes: 35 eyes each for groups of normal control, PACG and PAC patients. Researchers divided the PACG and PAC patients into groups of thick and thin CCT. Participants received 12 to 18 months of follow-up analysis, which included visual field progression assessment with mean Advanced Glaucoma Intervention Study (AGIS) score.

Results showed that the control group had a CCT of 540 ± 27.8 µm, while the PACG and PAC groups were significantly thinner, at 509.7 ± 27.4 µm and 516.8 ± 26.0 µm, respectively. Researchers also reported a statistically significant increase of mean AGIS score during the follow-up of the thin CCT PACG group, but no significant increases in the thick CCT PACG group or either PAC groups.

“The PACG and PAC group had statistically significantly thinner mean CCT compared with the control group,” the authors stated. “Thin CCT is associated with visual field progression based on the mean AGIS score in the PACG group, but not in the PAC group.” – by Chelsea Frajerman Pardes

Disclosure: The authors reported no relevant financial disclosures.

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Source: Healio