CHA Bundang Medical Center Announces Positive Results from Stem Cell Therapy for Macular Degeneration
by Lee Jae-seung
CHA Bundang Medical Center has become the first in Asia (the second in the world) to confirm that the transplantation of human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) cells is effective in treating age-related macular degeneration (AMD) and Stargardt disease (juvenile macular degeneration) without causing dangerous side effects. Hence CHA Bundang Medical Center is now on the fast track to developing the world’s first hESC-based therapeutic product.
The research team said four patients with age-related macular degeneration (AMD) did not show any signs of worrisome side effects after they had received their hESC-based cell therapy. And observing the four patients for a period of 12 months after the sub-retinal transplantation of hESC-derived retinal pigment epithelium (RPE) cells, the research team saw three of them show signs of visual improvements. The announcement of clinical results from this kind of hESCs-based therapy is the first in Asia and the second in the world after the US’s Ocata Therapeutics.
The hESC-based therapy used in their clinical trial was jointly developed by CHA Biotech and Ocata Therapeutics (formerly Advanced Cell Technology). And the Ministry of Food and Drug Safety (MFDS) of S. Korea approved the use of the hESC-based therapy in clinical trials in 2011. The hESC-based therapy revolves around having hESCs, obtained from the frozen embryos left over from fertility treatments, differentiate into RPE cells, which are then directly injected into the eyes of patients with AMD or Stargardt disease.
Read more: http://www.koreaittimes.com/story/48561/cha-bundang-medical-center-announces-positive-results-stem-cell-therapy-macular-degenera
Source: Korea IT Times