Cystoid macular edema or CME, is a painless disorder which affects the central retina or macula. When this condition is present, multiple cyst-like (cystoid) areas of fluid appear in the macula and cause retinal swelling or edema.

Euretina Lecture focuses on cystoid maculopathies and role of OCT

The Euretina Lecture this year focused on cystoid maculopathies and the revolution that OCT has brought into the understanding of cystoid macular changes.
The history of cystoid macular edema is closely linked to blood-retinal barrier (BRB) studies and the advent of fluorescein angiography at the end of the 1960s, Alain Gaudric, MD, emeritus professor in the Department of Ophthalmology at the Lariboisière Hospital, University of Paris 7, said.

The advent of OCT in 1995, which allowed the routine measurement of macular thickness, improved the understanding of cystoid macular changes in many ways, showing that CME is not always associated with leakage and BRB breakdown.

Treatments of diabetic macular edema, a major cause of vasogenic macular edema, may have limited functional effects when macular thickening results in relative retinal atrophy after fluid resorption. Atrophy may in fact be hidden in the macular thickening, Gaudric said……
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