1. Indocyanine green angiography is a diagnostic study where indocyanine green, a fluorescent dye, is injected intravenously, and observations of the retina are made at intervals as increasing intensity of retinal and choroidal circulation is displayed.- MDA

WAILEA, Hawaii – Indocyanine green angiography as an ancillary retina test is relevant in 2015 as a limited part of multimodal imaging, a presenter said.

“What we’ve learned from OCT is that our clinical impression is sometimes wrong, and having ancillary tests like angiography or OCT or fundus autofluorescence can confirm what we believe to be true is very helpful. They can rule out mimicking conditions and also give us a list of therapeutic options we can offer the patient,”Jay S. Duker, MD,said at Retina 2015. “What we’re really talking about for the average clinical practice is, is the retina thick or thin? And is the presence of choroidal neovascularization present or absent? Those are two big decision makers.” Furthermore, ancillary testing can assess whether treatment is adequate.

As an ancillary test, indocyanine green (ICG) angiography has better absorption through pigment and blood, it is highly protein bound, which equates to less leakage from the choriocapillaris, and it avoids the allergy concerns of fluorescein. The two major conditions that ICG angiography is used to diagnose are polypoidal choroidal vasculopathy and central serous chorioretinopathy, he said.
Disadvantages of ICG angiography are that it is not widely available, it is expensive, it is contraindicated in shellfish allergies, it has no utility in dry AMD and minimal benefit in wet AMD treated with anti-VEGF monotherapy, and there is no benefit in other retinal vascular disorders, such as diabetic retinopathy and retinal vein obstruction, according to the presentation…….
Read More: http://www.healio.com/ophthalmology/retina-vitreous/news/online/%7B17addc57-16d7-45b1-a1da-ae4b386ec799%7D/icg-angiography-clinically-useful-as-ancillary-test
Source: Healio