New eye layer has possible link to glaucoma

A new layer in the human cornea—discovered by researchers at The University of Nottingham last year—plays a vital role in the structure of the tissue that controls the flow of fluid from the eye, research has shown.

The findings, published in a paper in theBritish Journal of Ophthalmology, could shed new light on glaucoma, a devastating disease caused by defective drainage of fluid from the eye and the world’s second leading cause of blindness.

The latest research shows that the new layer, dubbed Dua’s Layer after the academic Professor Harminder Dua who discovered it, makes an important contribution to the sieve-like meshwork, the trabecular meshwork (TM), in the periphery of the cornea.
The TM is a wedge-shaped band of tissue that extends along the circumference of the angle of the anterior chamber of the eye. It is made of beams of collagen wrapped in a basement membrane to which trabecular cells and endothelial cells attach. The beams branch out randomly to form a ‘meshwork’.
Pressure within the eye is maintained by the balance of aqueous fluid production byeye tissue called the ciliary body and drainage principally through the TM to the canal of Schlemm, a circular channel in the angle of the eye.
Defective drainage through the TM is an important cause of glaucoma, a condition that leads to raised pressure in the eye that can permanently affect sight….
Source: Medical Express