Date:September 2, 2016

Source:McMaster

UniversitySummary: Researchers have re-invented the eye drop with technology that can deliver medicine much more efficiently, making life easier for patients. They have created microscopic packets of medicine that lodge themselves imperceptibly in the base of the tear film that makes up the wet surface of the eye.

No longer lost in the blink of an eye

It’s a problem as old and as aggravating as eye drops themselves: as soon as the medicine goes in, almost all of it washes right back out again.

Now, McMaster chemical engineer Heather Sheardown and the graduate students in her lab have developed a better way to deliver medicine to the surface of the eye.
They have created microscopic packets of medicine that lodge themselves imperceptibly in the base of the tear film that makes up the wet surface of the eye.
There, the molecular packets, or depots, dissolve gradually, releasing medicine slowly and making it possible for people with conditions such as dry eye and glaucoma — which require daily drops — to receive the same degree of treatment from using drops just once a week.
Sheardown, a Canada Research Chair in Ophthalmic Biomaterials and Scientific Director of the 20/20 NSERC Ophthalmic Materials Research Network, says that partners in the field had named the problem with conventional eye drops as one of the top issues in all of eye care.
The problem is that the eye does a good job of defending itself against foreign substances, making it difficult for the active ingredients in eye drops to do their work before the eye sheds them.
With conventional drops, 95 per cent of the medicine is typically lost before it has a chance to work, a frustrating inefficiency, especially for patients…….
Read more: https://www.sciencedaily.com/releases/2016/09/160902111617.htm
Source: Science Daily
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