Macular ischaemia, retinal thinning linked to reduced visual function in diabetic retinopathy

By Nikki Withers, medwireNews Reporter
Macular Degeneration Association can across this wonderful article explaining how macular ischemia and retinal thinning can reduce your visual function. They find this to be true in patients with diabetic retinopathy. 
Macular ischemia and retinal thinning are associated with reduced visual function in patients with diabetic retinopathy, research suggests. Previous studies have shown that age is a contributing factor to abnormalities associated with diabetic retinopathy. However, Dawn Sim (Moorfields Eye Hospital, London, UK) and colleagues believe that age alone is unlikely to be solely responsible.
To investigate further, the team used ultra-widefield fluorescein angiography (FA) to analyse the association between peripheral and central ischaemia in patients with diabetic retinopathy.
Specifically, they examined peripheral capillary nonperfusion, peripheral leakage, foveal avascular zone (FAZ) size and optical coherence tomography (OCT)-derived central macular thickness measurements and evaluated the visual significance of these parameters.
A total of 47 eyes from 47 patients were included in the study. The median age of the patients was 55 years.
Writing in the American Journal of Ophthalmology, Sim et al report that eyes with a high peripheral ischaemia index predominantly had a larger FAZ area than those with a low peripheral ischaemia index. And patients with a large FAZ area had a significantly thinner retina than those with a small FAZ area.
A large FAZ area was also moderately associated with a high peripheral leakage index but ….more:
source: News Medical