A B S T R A C T
Background: Patients with nAMD often have pathologically elevated homocysteine (Hcy) and increased retinal
venous pressure (RVP). We tested whether the administration of a specific vitamin preparation containing L-methylfolate
(Ocufolin forte) As an addition to anti-VEGF therapy, it reduces these two risk factors and favorably influences the disease course.

Methods: A total of 27 eyes/27 patients with intra- and subretinal fluid, Hcy above 12 μmol/L, RVP of at least 8
mm above the IOP, and an IOP between 10 and 20 mmHg was included in this study. All eyes received three

Injections of 0.05 ml aflibercept at one-month intervals as clinically indicated.

Read more: https://www.sciencedirect.com/science/article/pii/S2667376225000137

Source: Josef Flammer, Prof. Emeritus, University of Basel, Switzerland

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