Edited by Shrabasti Bhattacharya
TOPLINE:
Current smokers faced up to 12-fold higher risk for age-related macular degeneration, a threefold higher risk for primary open-angle glaucoma, and a fourfold higher risk for cataracts. The risk for certain ocular disorders persisted among individuals with a previous history of smoking.
METHODOLOGY:
- Researchers searched PubMed, Scopus, and Web of Science databases through December 2024 to conduct a systematic review and “meta–meta-analysis” of existing systematic reviews and meta-analyses related to smoking and the risk for ocular disorders associated with the habit.
- They included 12 meta-analyses of prospective cohort, cross-sectional, and case-control studies that assessed the risk for eye diseases associated with tobacco use among current, past, and former smokers compared with that among nonsmokers.
- The occurrence of the following ocular diseases linked to exposure to tobacco smoke was analyzed: Age-related macular degeneration, cataracts, primary open-angle glaucoma, dry eye disease, and toxic amblyopia.
TAKEAWAY:
- Current smokers had a significantly higher risk for age-related macular degeneration than nonsmokers (odds ratio [OR], 11.93; 95% CI, 4.40-32.33; risk ratio, 7.45; 95% CI, 4.09-13.57); individuals who had, at any point in their life, smoked tobacco products had an increased likelihood of developing age-related macular degeneration (OR, 7.09).
- Current smokers had approximately triple the risk for primary open-angle glaucoma (OR, 3.07; 95% CI, 2.07-4.54), with past smokers also having a similarly elevated risk (OR, 2.64; 95% CI, 2.33-3.00)…..
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Source: Medscape
Thank you, Dr. Semes, for sending us this article.