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Mar 26, 2024

Topical drop treatment for full-thickness macular hole closure

Wang and colleagues conducted a retrospective case series of patients with full-thickness macular holes.

A newly reported study, led by first author Jessie Wang, MD, found that topical therapy resulted in the closure of full-thickness macular holes in more than a third of patients; higher efficacy was seen in patients with smaller holes and in those without vitreomacular traction (VMT).1 Wang, from the Department of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, noted that this is the first study of the overall efficacy and clinical characteristics of successful macular hole closure using topical therapy.

Wang and colleagues conducted a retrospective case series of patients with full-thickness macular holes. One retina specialist had managed all the patients who were treated from 2017 to 2022.

The results showed that of the 168 patients identified, 71 had been treated with a steroid, carbonic anhydrase inhibitor, and nonsteroidal anti-inflammatory drops. The investigators included 49 of these patients in the analysis, while 22 were not included because of poor follow-up.

Read more: https://www.modernretina.com/view/topical-drop-treatment-for-full-thickness-macular-hole-closure

Source: Modern Retina

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