Dry Eye Rescue Is Offering Friends Of MDA A 20% Discount On All Products To Help With Your Eye Conditions

Click Here To Save Now

Aug 11, 2025

EyePoint completes enrollment in second phase 3 trial of sustained-release AMD therapy

ByJay S. Duker, MD
ByAlex Young
ByAnthony DeFino
Fact checked by Christine Klimanskis, ELS

Key takeaways:

  • More than 400 patients have been enrolled in the LUCIA trial investigating Duravyu.
  • EyePoint expects topline data from its phase 3 pivotal program in 2026.

LONG BEACH, Calif. — EyePoint Pharmaceuticals completed enrollment in the LUCIA trial, its second phase 3 trial of Duravyu in patients with wet age-related macular degeneration, according to a press release.

More than 400 patients have been enrolled in the trial and undergone randomization over the past 7 months. EyePoint’s first phase 3 trial of Duravyu, LUGANO, completed enrollment in May.

Both trials will assess the efficacy and safety of sustained-release Duravyu (vorolanib intravitreal insert) in patients with wet AMD who have been randomly assigned to receive either Duravyu 2.7 mg or on-label aflibercept control.

“These diseases are currently treated with short-acting ligand blockers, which do a very good job in the short term, but the big unmet need is prevention of visual loss in the long term,” Jay S. Duker, MD, president and CEO of EyePoint, told Healio at the American Society of Retina Specialists meeting.

Read more & Watch the Video: https://www.healio.com/news/ophthalmology/20250807/eyepoint-completes-enrollment-in-second-phase-3-trial-of-sustainedrelease-amd-therapy?utm_source=selligent&utm_medium=email&utm_campaign=20250810OSN&utm_content=20250810OSN

Source: Healio

Newsletter Sign-up

  • This field is for validation purposes and should be left unchanged.